A constant sense of hopelessness and despair is a sign you may have major depression, also known as clinical depression.

Major depressive disorder and dysthymia overlap in some ways. But there are key differences.

Psychomotor retardation is one of the main features of major depressive disorder (MDD) or, more simply, depression.

Depression can be severe enough that you’re unable to work anymore, or you’re unable to work at the pace you once were.

Your treatment plan for depression will depend on what type you have and how severe it is.

Depression can make you feel helpless. Taking charge of your treatment is one way to feel in control again. Here are some tips.

Psychotherapy is another tool in your toolkit to manage depression. And it works for lots of people.

Psychodynamic therapy helps patients explore the full range of their emotions, including feelings they may not be aware of.

Prescription meds that lift your mood are called antidepressants. It may take a while until you find one that's a good fit.

Many researchers believe that the benefits of antidepressants stem from how they affect certain brain circuits and chemicals.

Many people who could benefit from an antidepressant never try one, often because of fears about them, experts say.

Here are answers to common questions about antidepressants.

You may feel like your depression treatment isn't working at all. If so, you could have treatment-resistant depression (TRD).

Here are 10 questions to ask your doctor, with some answers you could expect to hear.

Psychotherapy is an effective treatment for clinical depression. On its own, it may not be enough to treat severe depression.

Researchers are working on new treatments for depression. These can offer hope to people who haven't been able to get relief.

Depression can make you feel powerless. But some simple lifestyle changes can help you get back on track.

There are several strategies and treatments that can help you manage your depression symptoms.

Even if you're already getting depression treatment with medicine and therapy, tending to your inner self can help you.

Without treatment, your depression can affect your work performance. You may not be engaged or may miss work.

Depression can sometimes be like other chronic illnesses that need ongoing treatment. This is called maintenance treatment.

Changing your lifestyle can have a big effect on your depression. However, it's not always easy to change our ways.

Does depression keep you from feeling in control of your days? You may find that having a routine helps with your symptoms.

For many people, depression can become a chronic or lifelong illness, with several relapses or recurrences.

The more you know about depression complications, the more you'll understand why it's important to not let it go untreated.

As a condition, depression doesn’t always fly solo. In fact, depression is actually a risk factor for many health problems.

Depression doesn't just cause physical symptoms; it can also increase your risk for -- or may worsen -- physical illnesses. 

It’s important to get help for depression. That’s because repeat episodes seem to damage your brain more and more over time.

The support and involvement of family and friends can be crucial in helping someone who is depressed.

Helping a loved one deal with depression can be the key to their recovery. It isn't always going to be easy.

Caring for someone you love with depression can lead to a lot of extra stress in your life.

Living with a chronic illness like depression can feel overwhelming. That's why it's important to seek depression support.

Whether you're newly diagnosed with depression or already in treatment, learn how to make the most of your doctor appointment.