Overview

Glucomannan is a dietary fiber usually made from the root of the konjac plant. It's historically been used as food and medicine in Asian cultures.

Glucomannan might work in the stomach and intestines by absorbing water to form a bulky fiber which treats constipation. It might also slow the absorption of sugar and cholesterol in the gut, helping to control sugar levels in people with diabetes and reduce cholesterol levels.

People commonly use glucomannan for constipation, diabetes, and high cholesterol. It's also used for high blood pressure, obesity, and many other conditions, but there is no good scientific evidence to support most of these uses.

Uses & Effectiveness ?

Possibly Effective for

  • Constipation. Taking glucomannan by mouth seems to relieve constipation in adults, but it's not clear if it helps in children.
  • Diabetes. Taking glucomannan by mouth seems to reduce cholesterol, blood sugar levels, and blood pressure in people with diabetes.
  • High levels of cholesterol and other fats (lipids) in the blood (hyperlipidemia). Taking glucomannan by mouth seems to improve cholesterol levels in people with or without high cholesterol.
There is interest in using glucomannan for a number of other purposes, but there isn't enough reliable information to say whether it might be helpful.

Side Effects

When taken by mouth: Glucomannan powder and flour are commonly consumed in foods. Glucomannan powder and capsules are possibly safe when taken with plenty of water for up to 4 months. But taking glucomannan products without water, especially as tablets, is possibly unsafe. These products might cause choking and other serious side effects when taken without water.

Special Precautions and Warnings

When taken by mouth: Glucomannan powder and flour are commonly consumed in foods. Glucomannan powder and capsules are possibly safe when taken with plenty of water for up to 4 months. But taking glucomannan products without water, especially as tablets, is possibly unsafe. These products might cause choking and other serious side effects when taken without water.
Pregnancy and breast-feeding: There isn't enough reliable information to know if glucomannan is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.

Children: Glucomannan powder and capsules are possibly safe for most children when taken with plenty of water for up to 4 months. But taking glucomannan products without water, especially as tablets, is likely unsafe. These products might cause choking and other serious side effects when taken without water.

Interactions ?

    Moderate Interaction

    Be cautious with this combination

  • Medications taken by mouth (Oral drugs) interacts with GLUCOMANNAN

    Taking glucomannan along with medications taken by mouth can decrease how much medicine the body absorbs. To prevent this interaction, take glucomannan at least one hour after medications you take by mouth.

Dosing

In foods, glucomannan powder or flour is commonly used as a thickening agent and as a source of dietary fiber.

As medicine, glucomannan has most often been used by adults in doses of 3-4 grams by mouth daily for up to 3 months. In children, glucomannan has most often been used in doses of 2-5 grams by mouth daily for up to 4 months. Speak with a healthcare provider to find out what dose might be best for a specific condition.
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CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version.
© Therapeutic Research Faculty 2020.