Uses
What is Aimovig used for?
Aimovig (erenumab-aooe) is commonly used to prevent migraine.
Aimovig may also be used for other conditions as determined by your healthcare provider.
How does Aimovig work (mechanism of action)?
Aimovig works by blocking a substance in the brain called calcitonin gene-related peptide (CGRP), which is involved in headache pain and can make headaches last longer. By blocking CGRP, Aimovig helps prevent migraine.
How is Aimovig supplied (dosage forms)?
Aimovig is available in the following dosage forms that are injected under the skin.
- 70 mg/mL solution for injection, prefilled autoinjectors (SureClick) and prefilled syringes
- 140 mg/mL solution for injection, prefilled autoinjectors (SureClick) and prefilled syringes
How should I store Aimovig?
Store Aimovig in the refrigerator, between 36 F to 46 F (2 C to 8 C). Do not freeze. Keep it in the original carton, which helps protect it from light.
Once removed from the refrigerator, you can store Aimovig at room temperature, up to 77 F (25 C), in the original carton, and use it within 7 days. If your medicine is left at room temperature for more than 7 days, throw it out. Once you store Aimovig at room temperature, you should not put it back in the refrigerator.
Side Effects
What are the most common side effects of Aimovig?
The most common side effects of Aimovig are listed below. Tell your healthcare provider if you have any of these side effects that bother you.
- Pain, swelling, or redness near the injection site
- Constipation
There may be other side effects of Aimovig that are not listed here. Contact your healthcare provider if you think you are having a side effect of a medicine. In the U.S., you can report side effects to the FDA at www.fda.gov/medwatch or by calling 800-FDA-1088. In Canada, you can report side effects to Health Canada at www.health.gc.ca/medeffect or by calling 866-234-2345.
What are the serious side effects of Aimovig?
While less common, the most serious side effects of Aimovig are described below, along with what to do if they happen.
Severe Allergic Reactions. Aimovig may cause allergic reactions, which can be serious. Stop using Aimovig and get help right away if you have any of the following symptoms of a serious allergic reaction.
- Breathing problems or wheezing
- Racing heart
- Fever or general ill feeling
- Swollen lymph nodes
- Swelling of the face, lips, mouth, tongue, or throat
- Trouble swallowing or throat tightness
- Itching, skin rash, or pale red bumps on the skin called hives
- Nausea or vomiting
- Dizziness, feeling lightheaded, or fainting
- Stomach cramps
- Joint pain
Severe Constipation. Aimovig may cause severe constipation. Some people needed to go to the hospital. Call your healthcare provider right away if you have constipation and any of the following symptoms.
- Severe belly pain that will not go away
- Vomiting
- Swelling or bloating of your stomach area
Increased Blood Pressure (Hypertension). Aimovig may increase your blood pressure or make it worse if you have a history of high blood pressure. Call your healthcare provider if your blood pressure increases while using this medicine.
If you measure your blood pressure and the top number (systolic) is 180 mm Hg or higher or the bottom number (diastolic) is 120 mm Hg or higher, get medical attention right away. Increases in blood pressure may not be noticeable but look out for any of the following symptoms of severely high blood pressure.
- Sudden severe headache
- Chest pain
- Dizziness or confusion
- Trouble breathing
- Nausea/vomiting
- Blurry or other changes to vision
- Anxiety
- Buzzing in the ears
- Nosebleed
- Feeling of skipped heartbeats
Warnings & Precautions
Who should not use Aimovig?
Allergies to Ingredients. People who are allergic to any of the following should not use Aimovig.
- Erenumab-aooe
- Aimovig
- Any of the ingredients in the specific product dispensed
Your pharmacist can tell you all of the ingredients in Aimovig.
What should I know about Aimovig before using it?
Do not use Aimovig unless it has been prescribed to you by a healthcare provider. Use it as prescribed.
Do not share Aimovig with other people, even if they have the same condition as you. It may harm them.
Keep Aimovig out of the reach of children. If you keep the medicine in a refrigerator, take special precautions to keep it away from children who also use the refrigerator.
If you take Aimovig out of the refrigerator just before injecting it, let it sit at room temperature for at least 30 minutes before injecting it. Do not heat in the microwave or in hot water. During this time, protect from sunlight.
This medicine is injected under the skin. Make sure that you or a caregiver understand how to properly prepare and use Aimovig. If you have any questions, talk to your healthcare provider.
Do not shake Aimovig.
Each injection is for one time use. Discard the prefilled syringe or autoinjector properly in a sharps container after one use.
What should I tell my healthcare provider before using Aimovig?
Tell your healthcare provider about all of your health conditions and any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. This will help them determine if Aimovig is right for you.
In particular, make sure that you discuss any of the following.
Hypertension (High Blood Pressure). Aimovig may cause high blood pressure, or if you already have high blood pressure, Aimovig may cause it to worsen. Some people needed to take medication or go to the hospital. This can happen at any time while using Aimovig, but it often occurs within 7 days of the first dose. Ask your healthcare provider about monitoring your blood pressure while using Aimovig.
Pregnancy. It is not known if or how Aimovig could affect pregnancy or harm an unborn baby. Tell your healthcare provider if you are or plan to become pregnant. If you become pregnant while using Aimovig, you can register for the Genesis Pregnancy Registry by calling 833-244-4083 or at www.genesispregnancyregistry.com. This registry collects safety information about the use of migraine medicines during pregnancy.
Breastfeeding. It is not known if Aimovig passes into breast milk. Tell your healthcare provider if you are breastfeeding or plan to breastfeed. Your healthcare provider will advise you if you should take Aimovig while breastfeeding.
How can I get more information about Aimovig?
For more information about Aimovig, you can visit the manufacturer’s website at www.aimovig.com or call them at 833-AIMOVIG (833-246-6844).
Interactions
Does Aimovig interact with foods or drinks?
There are no known interactions between Aimovig and foods or drinks.
There are no known interactions between Aimovig and alcohol. However, alcohol can trigger migraine attacks in some people. Consult your healthcare provider for more information and medical advice.
Does Aimovig interact with other medicines (drug interactions)?
There are no known interactions between Aimovig and other medicines. Always tell your healthcare provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using.
Overdose/Missed Dose
What should I do if I accidentally use too much Aimovig?
If you or someone else has used too much Aimovig, get medical help right away, call 911, or contact a Poison Control center at 800-222-1222.
What should I do if I miss a dose of Aimovig?
If you miss a dose, use it as soon as you remember. Your next dose will be 1 month later. Do not take double or extra doses.