Uses
What is Durysta used for?
Durysta (bimatoprost) is commonly used to reduce increased pressure in the eye in people with either open-angle glaucoma or ocular hypertension.
Durysta may also be used for other conditions as determined by your healthcare provider.
How does Durysta work (mechanism of action)?
Durysta is part of a group of medicines called prostaglandin analogs. People with glaucoma or ocular hypertension have high intraocular pressure (IOP), or high pressure inside the eye, which increases the risk for vision loss and nerve damage in the eyes. Durysta is an implant that is injected into the eye by a healthcare provider. It works by helping the fluid in the eye drain out, which helps decrease IOP.
How is Durysta supplied (dosage forms)?
Durysta is available as a 10 mcg implant that is inserted into the eye.
How should I store Durysta?
Durysta is given by a healthcare provider in a hospital or clinic. You will not store it at home.
Side Effects
What are the most common side effects of Durysta?
The most common side effects of Durysta are listed below. Tell your healthcare provider if you have any of these side effects that bother you.
- Eye redness
- Feeling like something is in the eye
- Eye pain or irritation
- Dry eyes
- Sensitivity to light
- A red patch on the white part of the eye
- Blurry vision
- Headache
- Inflammation of the iris, the colored part of the eye
There may be other side effects of Durysta that are not listed here. Contact your healthcare provider if you think you are having a side effect of a medicine. In the U.S., you can report side effects to the FDA at www.fda.gov/medwatch or by calling 800-FDA-1088. In Canada, you can report side effects to Health Canada at www.health.gc.ca/medeffect or by calling 866-234-2345.
What are the serious side effects of Durysta?
While less common, the most serious side effects of Durysta are described below, along with what to do if they happen.
Severe Allergic Reactions. Durysta may cause allergic reactions, which can be serious. Get help right away if you have any of the following symptoms of a serious allergic reaction.
- Breathing problems or wheezing
- Racing heart
- Fever or general ill feeling
- Swollen lymph nodes
- Swelling of the face, lips, mouth, tongue, or throat
- Trouble swallowing or throat tightness
- Itching, skin rash, or pale red bumps on the skin called hives
- Nausea or vomiting
- Dizziness, feeling lightheaded, or fainting
- Stomach cramps
- Joint pain
Increased Brown Coloring of the Iris. Durysta may cause the colored part of the eye called the iris to increase in brown color. This effect may take months to years to occur, and may be permanent. Keep all appointments to have your eyes checked.
Eye Inflammation and Macular Edema. Durysta may cause inflammation in your eye, including a problem called macular edema. Macular edema is swelling from too much fluid in part of your eye called the retina. This can affect your vision. If you have any vision changes, call your healthcare provider right away.
Warnings & Precautions
Who should not use Durysta?
Allergies to Ingredients. People who are allergic to any of the following should not use Durysta.
- Bimatoprost
- Durysta
- Any of the ingredients in Durysta
Your healthcare provider can tell you all of the ingredients in Durysta.
Eye Infections. People with infections of the eye or around the eye should not receive Durysta.
Corneal Endothelial Cell Dystrophy. People with a condition called corneal endothelial cell dystrophy (Fuch’s dystrophy) should not use Durysta. Corneal endothelial cell dystrophy is a condition where the cells that keep the cornea (the clear front part of the eye) healthy start to break down, causing vision problems.
Previous Corneal Transplantation. People who have had a previous corneal transplantation, or endothelial cell transplants such as Descemet’s Stripping Automated Endothelial Keratoplasty (DSAEK), should not use Durysta.
Absent or Ruptured Posterior Lens Capsule. The posterior lens capsule is a layer of tissue that holds the lens in place and maintains its shape. People with a ruptured or absent posterior lens capsule should not use Durysta.
What should I know about Durysta before using it?
Do not lie down for at least an hour after you receive Durysta. The medicine needs to settle in the right place in your eye.
Your eye will likely be red and somewhat uncomfortable after you receive Durysta. However, if your eye becomes more red and uncomfortable or if you develop eye pain, sensitivity to light, or vision changes, get medical help from your eye doctor right away.
What should I tell my healthcare provider before using Durysta?
Tell your healthcare provider about all of your health conditions and any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. This will help them determine if Durysta is right for you.
In particular, make sure that you discuss any of the following.
Current and past health conditions. Tell your healthcare provider if you have any of the following.
- Any type of eye problem, including uveitis (inflammatory conditions that affect the middle part of the eye), macular edema, narrow angles, obstruction (a blockage), eye pressure problems, no lens (aphakia), or problems with your eye lens
- Diabetes
- A history of eye surgery
Pregnancy. It is not known if or how Durysta could affect pregnancy or harm an unborn baby. Tell your healthcare provider if you are or plan to become pregnant.
Breastfeeding. It is not known if Durysta passes into breast milk. Tell your healthcare provider if you are breastfeeding or plan to breastfeed. Your healthcare provider will advise you if you should use Durysta while breastfeeding.
How can I get more information about Durysta?
For more information about Durysta, you can visit the manufacturer’s website at www.durysta.com or call them at 833-DURYSTA (833-387-9782).
Interactions
Does Durysta interact with foods or drinks?
There are no known interactions between Durysta and foods or drinks.
It is unknown if drinking alcohol will affect Durysta.
Does Durysta interact with other medicines (drug interactions)?
There are no known interactions between Durysta and other medicines. Always tell your healthcare provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using.
Overdose/Missed Dose
What should I do if I accidentally use too much Durysta?
Durysta is an implant that is inserted into the eye by a healthcare provider. You cannot use too much.
What should I do if I miss a dose of Durysta?
Durysta is an implant that is inserted into the eye by a healthcare provider. If you already received Durysta, you will not get another in the same eye.
Are you currently using Durysta (bimatoprost)?
This survey is being conducted by the WebMD marketing sciences department.