Uses
What is Adbry used for?
Adbry (tralokinumab) is commonly used to treat a skin condition called atopic dermatitis (eczema). Adbry may be used if your eczema is moderate to severe and topical treatments that you apply to the skin have not helped enough or cannot be used.
Adbry may also be used for other conditions as determined by your healthcare provider.
How does Adbry work (mechanism of action)?
Skin lesions, itchiness, and other symptoms of atopic dermatitis (eczema) are caused in part by inflammation. Adbry works by blocking a protein that triggers inflammation.
How is Adbry supplied (dosage forms)?
Adbry is available in the following dosage forms that are injected under the skin (subcutaneous).
- 150 mg/mL solution for injection, prefilled syringe
- 300 mg/2 mL solution for injection, autoinjector
How should I store Adbry?
Store Adbry in the refrigerator, between 36 F to 46 F (2 C to 8 C).
You may store Adbry at room temperature, up to 86 F (30 C), for a maximum of 14 days. Do not place Adbry back in the refrigerator after it has been left out at room temperature. Dispose of any unused Adbry if it is kept at room temperature for longer than 14 days. See the Warnings & Precautions section for information about disposing of Adbry.
Store Adbry in the original carton to protect it from light. Do not freeze, shake, or place it in direct sunlight.
Side Effects
What are the most common side effects of Adbry?
The most common side effects of Adbry are listed below. Tell your healthcare provider if you have any of these side effects that bother you.
- Infection in the nose or throat, or common cold symptoms
- Itchy, inflamed, or red eyes (see below)
- Pain, itching, swelling, or redness near the injection site
- High eosinophil count (a type of white blood cell)
There may be other side effects of Adbry that are not listed here. Contact your healthcare provider if you think you are having a side effect of a medicine. In the U.S., you can report side effects to the FDA at www.fda.gov/medwatch or by calling 800-FDA-1088. In Canada, you can report side effects to Health Canada at www.health.gc.ca/medeffect or by calling 866-234-2345.
What are the serious side effects of Adbry?
While less common, the most serious side effects of Adbry are described below, along with what to do if they happen.
Severe Allergic Reactions. Adbry may cause allergic reactions, which can be serious. Stop using Adbry and get help right away if you have any of the following symptoms of a serious allergic reaction.
- Breathing problems or wheezing
- Racing heart
- Fever or general ill feeling
- Swollen lymph nodes
- Swelling of the face, lips, mouth, tongue, or throat
- Trouble swallowing or throat tightness
- Itching, skin rash, or pale red bumps on the skin called hives
- Nausea or vomiting
- Dizziness, feeling lightheaded, or fainting
- Stomach cramps
- Joint pain
Severe Eye Problems. Adbry may cause eye problems, such as pink eye (conjunctivitis) and inflammation of the cornea (keratitis). Contact your healthcare provider right away if you have any of the following symptoms.
- Eye redness, itchiness, or pain
- Swollen or itchy eyelids
- Feeling like you have something in your eye
- Eye dryness, watering, or discharge
- Vision changes, such as blurry vision or sensitivity to light
Warnings & Precautions
Who should not use Adbry?
Allergies to Ingredients. People who are allergic to any of the following should not use Adbry.
- Adbry
- Tralokinumab-ldrm
- Any of the ingredients in the specific product dispensed
Your pharmacist can tell you all of the ingredients in Adbry.
What should I know about Adbry before using it?
Do not use Adbry unless it has been prescribed to you by a healthcare provider. Use it as prescribed.
Do not share Adbry with other people, even if they have the same condition as you. It may harm them.
Keep Adbry out of the reach of children. Since this medicine may be stored in a refrigerator, take special care to keep it away from children who also use the refrigerator.
This medicine is injected under the skin. Make sure that you or a caregiver understands how to properly prepare and use Adbry. If you have any questions, talk to your healthcare provider.
Adbry should be disposed of in a sharps container to protect others from contact with the attached needle. A healthcare professional can advise you on how to dispose of Adbry safely.
What should I tell my healthcare provider before using Adbry?
Tell your healthcare provider about all of your health conditions and any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. This will help them determine if Adbry is right for you.
In particular, make sure that you discuss any of the following.
Parasite Infection. Adbry may make it more difficult for your body to fight certain parasite infections caused by worms (helminths). Tell your healthcare provider if you have a worm infection so it can be treated before you start Adbry. If you become infected with a worm, such as pinworm, tell your healthcare provider. They may stop your Adbry treatment until after the worm infection is treated.
Other Current and Past Health Conditions. Tell your healthcare provider if you have any eye problems.
Vaccines. Receiving a live vaccine while using Adbry may raise your risk of infection. Tell your healthcare provider about any vaccines you recently received or if you have any vaccines scheduled. They will advise you if you should wait to start your Adbry treatment until after you get any necessary vaccines.
Pregnancy. It is not known if or how Adbry could affect pregnancy or harm an unborn baby. Tell your healthcare provider if you are or plan to become pregnant. They will advise you if you should use Adbry while you are pregnant or trying to get pregnant. If you become pregnant while using this medicine, you can register for the Adbry Pregnancy Registry by calling 877-311-8972 or visiting mothertobaby.org/ongoing-study/adbry-tralokinumab. This registry collects safety information about using Adbry during pregnancy.
Breastfeeding. It is not known if Adbry passes into breast milk. Tell your healthcare provider if you are breastfeeding or plan to breastfeed. Your healthcare provider will advise you if you should use Adbry while breastfeeding.
How can I get more information about Adbry?
For more information about Adbry, you can visit the manufacturer’s website at www.adbry.com or call them at 877-494-4536.
Interactions
Does Adbry interact with foods or drinks?
There are no known interactions between Adbry and foods or drinks.
It is unknown if drinking alcohol will affect Adbry.
Does Adbry interact with other medicines (drug interactions)?
There are no known interactions between Adbry and other medicines. Always tell your healthcare provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using.
Overdose/Missed Dose
What should I do if I accidentally use too much Adbry?
If you or someone else has used too much Adbry, get medical help right away, call 911, or contact a Poison Control center at 800-222-1222.
What should I do if I miss a dose of Adbry?
If you miss a dose, use it as soon as possible. Then continue Adbry at your usual dose at the next regular time.
Are you currently using Adbry (tralokinumab-ldrm)?
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