2017-18 NCAA Banned Drugs List. National Collegiate Athletic Association (NCAA), June 5, 2017. https://www.ncaa.org/2017-18-ncaa-banned-drugs-list. Accessed: Sept 7, 2017
Bedi H, Hammond C, Sanders D, Yang HM, Yoshida EM. Drug-induced liver injury from enobosarm (ostarine), a selective androgen receptor modulator. ACG Case Rep J 2021;8(1):e00518. View abstract.
Coss CC, Jones A, Dalton JT. Pharmacokinetic drug interactions of the selective androgen receptor modulator GTx-024 (enobosarm) with itraconazole, rifampin, probenecid, celecoxib and rosuvastatin. Invest New Drugs 2016;34(4):458-67. View abstract.
Dalton JT, Barnette KG, Bohl CE, et al. The selective androgen receptor modulator GTx-024 (enobosarm) improves lean body mass and physical function in healthy elderly men and postmenopausal women: results of a double-blind, placebo-controlled phase II trial. J Cachexia Sarcopenia Muscle 2011;2(3):153-61. View abstract.
Dart DA, Kandil S, Tommasini-Ghelfi S, et al. Novel trifluoromethylated enobosarm analogues with potent antiandrogenic activity in vitro and tissue selectivity in vivo. Mol Cancer Ther 2018;17(9):1846-58. View abstract.
Dobs AS, Boccia RV, Croot CC, et al. Effects of enobosarm on muscle wasting and physical function in patients with cancer: a double-blind, randomised controlled phase 2 trial. Lancet Oncol 2013;14(4):335-45. View abstract.
Dubois V, Simitsidellis I, Laurent MR, et al. Enobosarm (GTx-024) modulates adult skeletal muscle mass independently of the androgen receptor in the satellite cell lineage. Endocrinology 2015;156(12):4522-33. View abstract.
Dynamic Technical Formulations, LLC. Issues a Voluntary Nationwide Recall of Tri-Ton Due to the Presence of Andarine and Ostarine. FDA Recalls, Market Withdrawals, & Safety Alerts, May 19, 2017. https://www.fda.gov/Safety/Recalls/ucm559700.htm?source=govdelivery&utm_medium=email&utm_source=govdelivery. Accessed: Sept 7, 2017.
FDA. FDA Warns against using SARMs in body building products. October 2017. Available at: https://www.fda.gov/newsevents/newsroom/fdainbrief/ucm583021.htm.
Gheddar L, Raul JS, Kintz P. Development and validation of SARMs and metabolic modulators screening in hair using UHPLC-MS/MS: Application to a doping case and first identification of S23 in authentic human hair. J Chromatogr B Analyt Technol Biomed Life Sci 2021;1187:123048. View abstract.
Kintz P, Gheddar L, Paradis C, et al. Peroxisome Proliferator-Activated Receptor Delta Agonist (PPAR- d) and Selective Androgen Receptor Modulator (SARM) Abuse: Clinical, Analytical and Biological Data in a Case Involving a Poisonous Combination of GW1516 (Cardarine) and MK2866 (Ostarine). Toxics 2021;9(10):251. View abstract.
Komrakova M, Büchler G, Böker KO, et al. A combined treatment with selective androgen and estrogen receptor modulators prevents bone loss in orchiectomized rats. J Endocrinol Invest 2022;45(12):2299-2311. View abstract.
Komrakova M, Furtwängler J, Hoffmann DB, Lehmann W, Schilling AF, Sehmisch S. The selective androgen receptor modulator ostarine improves bone healing in ovariectomized rats. Calcif Tissue Int 2020;106(2):147-157. View abstract.
Komrakova M, Nagel J, Hoffmann DB, Lehmann W, Schilling AF, Sehmisch S. Effect of selective androgen receptor modulator enobosarm on bone healing in a rat model for aged male osteoporosis. Calcif Tissue Int 2020;107(6):593-602. View abstract.
Leciejewska N, Kolodziejski PA, Sassek M, Nogowski L, Malek E, Pruszynska-Oszmalek E. Ostarine-Induced Myogenic Differentiation in C2C12, L6, and Rat Muscles. Int J Mol Sci 2022;23(8):4404. View abstract.
Leciejewska N, Pruszynska-Oszmalek E, Bien J, Nogowski L, Kolodziejski PA. Effect of ostarine (enobosarm/GTX024), a selective androgen receptor modulator, on adipocyte metabolism in Wistar rats. J Physiol Pharmacol 2019;70(4). View abstract.
Roch PJ, Henkies D, Carstens JC, et al. Ostarine and ligandrol improve muscle tissue in an ovariectomized rat model. Front Endocrinol (Lausanne) 2020;11:556581. View abstract.
Roch PJ, Wolgast V, Gebhardt MM, et al. Combination of selective androgen and estrogen receptor modulators in orchiectomized rats. J Endocrinol Invest 2022;45(8):1555-1568. View abstract.
Selective Androgen Receptor Modulators (SARMs) - A Prohibited Class of Anabolic Agents. U.S. Anti-Doping Agency, November 18, 2015. https://www.usada.org/selective-androgen-receptor-modulators-sarms-prohibited-class-anabolic-agencts/. Accessed: August 30, 2017.
Thevis M, Geyer H, Thomas A, Schänzer W. Trafficking of drug candidates relevant for sports drug testing: detection of non-approved therapeutics categorized as anabolic and gene doping agents in products distributed via the Internet. Drug Test Anal 2011;3(5):331-6. View abstract.
USADA. Athlete Advisory: Ostarine in Supplements. July 2017. Available at: https://www.usada.org/growing-evidence-ostarine-athlete-risk/.
Van Wagoner RM, Eichner A, Bhasin S, Deuster PA, Eichner D. Chemical composition and labeling of substances marketed as selective androgen receptor modulators and sold via the internet.
JAMA 2017;318(20):2004-10.
View abstract.
WADA. What is prohibited. 2019 list of prohibited substances and methods. Available at: https://www.wada-ama.org/en/content/what-is-prohibited/.
Warning Letter: Infantry Labs LLC 10/23/17. FDA Inspections, Compliance, Enforcement, and Criminal Investigations, October 23, 2017. https://www.fda.gov/iceci/enforcementactions/warningletters/2017/ucm582685.htm. Accessed: November 1, 2017
Warning Letter: Ironmag Labs 10/23/17. FDA Inspections, Compliance, Enforcement, and Criminal Investigations, October 23, 2017. https://www.fda.gov/iceci/enforcementactions/warningletters/2017/ucm582464.htm Accessed: November 1, 2017
Warning Letter: Panther Sports Nutrition 10/23/17. FDA Inspections, Compliance, Enforcement, and Criminal Investigations, October 23, 2017. https://www.fda.gov/iceci/enforcementactions/warningletters/2017/ucm581630.htm. Accessed: November 1, 2017
Weinblatt D, Roy S. Drug-Induced Liver Injury Secondary to Enobosarm: A Selective Androgen Receptor Modulator. J Med Cases 2022;13(5):244-248. View abstract.