ANGELICA ARCHANGELICA: Overview, Uses, Side Effects, Precautions, Interactions, Dosing and Reviews

Overview

Angelica archangelica is an herb that grows up to 250 cm tall. The root, seed, leaf, and fruit have been used historically in Nordic folk medicine.

Angelica archangelica contains chemicals that might kill cancer cells and fungus, reduce anxiety, and settle the stomach.

People use Angelica archangelica for indigestion, quitting smoking, excessive urination at night, decline in memory and thinking skills, rheumatoid arthritis (RA), and many other conditions, but there is no good scientific evidence to support these uses.

Uses & Effectiveness ?

We currently have no information for ANGELICA ARCHANGELICA overview.

Side Effects

When taken by mouth: Angelica archangelica is commonly consumed in foods. There isn't enough reliable information to know if Angelica archangelica is safe as a medicine. Angelica archangelica might make your skin more sensitive to sunlight. Wear sunblock if you use it.

When applied to the skin: There isn't enough reliable information to know if Angelica archangelica is safe or what the side effects might be.

Special Precautions and Warnings

Pregnancy and breast-feeding: There isn't enough reliable information to know if Angelica archangelica is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.

Interactions ?

We currently have no information for ANGELICA ARCHANGELICA overview.

Dosing

There isn't enough reliable information to know what an appropriate dose of Angelica archangelica might be. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult a healthcare professional before using.

View References

REFERENCES:

Choi HK, Jung GW, Moon KH, et al. Clinical study of SS-Cream in patients with lifelong premature ejaculation. Urology 2000;55:257-61. View abstract.

Cordell B, Buckle J. The effects of aromatherapy on nicotine craving on a U.S. campus: a small comparison study. J Altern Complement Med. 2013 Aug;19(8):709-13. doi: 10.1089/acm.2012.0537. Epub 2013 Mar 28. View abstract.

Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182

Entman ML, Cook JW Jr, Bressler R. The influence of ouabain and alpha angelica lactone on calcium metabolism of dog cardiac microsomes. J Clin Invest 1969;48:229-34. View abstract.

Holtmann G, Madisch A, Juergen H, et al. A double-blind, randomized, placebo-controlled trial on the effects of an herbal preparation in patients with functional dyspepsia [Abstract]. Ann Mtg Digestive Disease Week 1999 May.

Kudoh C, Hori T, Yasaki S, Ubagai R, Tabira T. Effects of ferulic acid and Angelica archangelica extract (Feru-guard) on mild cognitive impairment: a multicenter, randomized, double-blind, placebo-controlled prospective trial. J Alzheimers Dis Rep. 2020;4(1):393-8. View abstract.

Kumar D, Bhat ZA, Kumar V, Shah MY. Coumarins from Angelica archangelica Linn. and their effects on anxiety-like behavior. Prog Neuropsychopharmacol Biol Psychiatry. 2013;40:180-6. View abstract.

Kumar D, Bhat ZA. Anti-anxiety Activity of Methanolic Extracts of Different Parts of Angelica archangelica Linn. J Tradit Complement Med. 2012 Jul;2(3):235-41. View abstract.

Liu JH, Xu SX, Yao XS, Kobayashi H. Angelol-type coumarins from Angelica pubescence F. biserrata and their inhibitory effect on platelet aggregation. Phytochem 1995;39:1099-101. View abstract.

Lo AC, Chan K, Yeung JH, Woo KS. Danggui (Angelica sinensis) affects the pharmacodynamics but not the pharmacokinetics of warfarin in rabbits. Eur J Drug Metab Pharmacokinet 1995;20:55-60. View abstract.

Madisch A, Holtmann G, Mayr G, et al. Treatment of functional dyspepsia with a herbal preparation. A double-blind, randomized, placebo-controlled, multicenter trial. Digestion 2004;69:45-52. View abstract.

Melzer J, Rosch W, Reichling J, et al. Meta-analysis: phytotherapy of functional dyspepsia with the herbal drug preparation STW 5 (Iberogast). Aliment Pharmacol Ther 2004;20:1279-87. View abstract.

Muller M, Byres M, Jaspars M. et al. 2D NMR spectroscopic analyses of archangelicin from the seeds of Angelica archangelica. Acta Pharm 2004;54:277-85. View abstract.

Ojala T, Vuorela P, Kiviranta J, et al. A bioassay using Artemia salina for detecting phototoxicity of plant coumarins. Planta Med 1999;65:715-8. View abstract.

Prakash B, Singh P, Goni R, Raina AK, Dubey NK. Efficacy of Angelica archangelica essential oil, phenyl ethyl alcohol and a- terpineol against isolated molds from walnut and their antiaflatoxigenic and antioxidant activity. J Food Sci Technol. 2015;52(4):2220-8. View abstract.

Sigurdsson S, Geirsson G, Gudmundsdottir H, Egilsdottir PB, Gudbjarnason S. A parallel, randomized, double-blind, placebo-controlled study to investigate the effect of SagaPro on nocturia in men. Scand J Urol. 2013;47(1):26-32. View abstract.

Sigurdsson S, Ogmundsdottir HM, Gudbjarnason S. Antiproliferative effect of Angelica archangelica fruits. Z Naturforsch [C] 2004;59:523-7. View abstract.

Sigurdsson S, Ogmundsdottir HM, Hallgrimsson J, Gudbjarnason S. Antitumour activity of Angelica archangelica leaf extract. In Vivo 2005;19:191-4. View abstract.

Storr M, Sibaev A, Weiser D, et al. Herbal extracts modulate the amplitude and frequency of slow waves in circular smooth muscle of mouse small intestine. Digestion 2004;70:257-64. View abstract.

Watanabe Y, Nessa N, Toba H, Kobara M, Nakata T. Angelica acutiloba Exerts Antihypertensive Effect and Improves Insulin Resistance in Spontaneously Hypertensive Rats Fed with a High-Fat Diet. Pharmacology 2022;107(3-4):188-196. View abstract.

Yeh ML, Liu CF, Huang CL, Huang TC. Hepatoprotective effect of Angelica archangelica in chronically ethanol-treated mice. Pharmacology 2003;68:70-3. View abstract.

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CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

This copyrighted material is licensed from Therapeutic Research Center, LLC. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version.
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ANGELICA ARCHANGELICA - Uses, Side Effects, and More